Optimal Capacity of the Blume-Emery-Griffiths perceptron

A Blume-Emery-Griffiths perceptron model is introduced and its optimal capacity is calculated within the replica-symmetric Gardner approach, as a function of the pattern activity and the imbedding stability parameter. The stability of the replica-symmetric approximation is studied via the analogue of the Almeida-Thouless line. A comparison is made with other three-state perceptrons.Comment: 10 pages, 8 figure

Mathematical models in physiology

Computational modelling of biological processes and systems has witnessed a remarkable development in recent years. The search-term (modelling OR modeling) yields over 58000 entries in PubMed, with more than 34000 since the year 2000: thus, almost two-thirds of papers appeared in the last 5–6 years, compared to only about one-third in the preceding 5–6 decades.\ud \ud The development is fuelled both by the continuously improving tools and techniques available for bio-mathematical modelling and by the increasing demand in quantitative assessment of element inter-relations in complex biological systems. This has given rise to a worldwide public domain effort to build a computational framework that provides a comprehensive theoretical representation of integrated biological function—the Physiome.\ud \ud The current and next issues of this journal are devoted to a small sub-set of this initiative and address biocomputation and modelling in physiology, illustrating the breadth and depth of experimental data-based model development in biological research from sub-cellular events to whole organ simulations